Does CBD work for dog

Does CBD Work for Dogs?

Does CBD work for dog

Topper, a 7-year-old Ibizan Hound, could hardly walk after being diagnosed with severe arthritic changes due to Valley fever. “The pain became so debilitating he had to be carried outside to eat, drink, or use the bathroom,” recalls owner Christy Moore. “He was on pain medication but it wasn’t working. A friend recommended pet CBD. Within three days he could walk on all four legs and I was crying tears of joy. It was the miracle we needed.”

Lady Amelthia, a Greyhound, was so petrified of thunderstorms she would destroy a crate to escape. “Holding her only made her claw to get away. A Thunder Shirt reduced her from 100 to 90 on the anxiety scale,” recalls owner Jenn Boswell, director of the Alabama Greyhound Adoption Center. “Veterinary-prescribed trazodone took it down to a 50. Tried three drops of CBD oil and it went down to a 5.”

Success stories abound of dogs overcoming anxiety, slowing seizures, and even beating cancer due to cannabidiol (CBD), one of more than 100 cannabinoids found in cannabis plants. But how can one substance help so many unrelated problems? Or can it?

Cannabinoids are substances including CBD and THC that mimic the endocannabinoid chemicals naturally produced in all vertebrates. Receptors for endocannabinoids are found throughout the body. The body’s endocannabinoids act as master regulators that signal other systems when to speed up or slow down, working to stabilize the body and return it to homeostasis. Cannabinoids from the cannabis plant affect these same receptors, each in slightly different ways. For example, THC causes a high, while CBD does not.

Is It Harmful?

Unlike THC, which can cause toxicity and even death in dogs when given at prescribed human dosages, the worst CBD has been documented to do is cause diarrhea and changes in some liver enzyme values after several weeks. The main concern with CBD is that it inhibits a chemical in the body called cytochrome P450 that is responsible for metabolizing most drugs. If a drug’s efficacy depends on its metabolized product, CBD could render it less effective. If a drug’s safety depends on it being cleared from the body within a certain time frame, CBD could cause it to build up to toxic levels. Never give your dog CBD without your veterinarian’s knowledge if your dog is taking other drugs.

Cute rough collie dog standing on lawn near rubber ball

Does It Work?

Research with dogs is still scarce, but there’s a huge body of research (about 23,000 published papers!) looking at CBD’s effect on laboratory animals and humans, with encouraging results for pain, especially arthritic pain, itchiness, anxiety, and cancer, all of which have at least one canine study as well. The results in dogs? It depends.

Arthritis: Several studies have looked at CBD’s effectiveness against arthritic pain, all with positive results. A Cornell University College of Veterinary Medicine study found dogs given CBD at a rate of 4.4 mg per pound twice daily for a month showed significant improvement in pain relief and quality of life. Lead investigator Joe Wakshlag, DVM, Ph.D., DACVN, said that some dogs were initially so decrepit that their owners considered euthanasia, but that after just days on CBD they were trotting around and even climbing stairs. A Baylor University study found similar improvement, adding that CBD worked better when delivered in a liposomal formulation.

Itchiness: Two recent double-blind, placebo-controlled dog studies report CBD significantly reduces itchiness. An Australian study conducted by the company CannPal found their CBD product reduced itchiness, inflammation, and skin lesions by 51 percent after eight weeks of treatment. An American study conducted by the company ElleVet found their product, which combines CBD with another cannabinoid, CBDA, significantly reduced owners’ reports of itchiness.

Cancer: Cannabinoids are reported to induce cancer-cell death and prevent metastasis. In a Cornell University study of CBD, dogs, and cancer, researchers found CBD along with a standard chemotherapy drug reduced cancer-cell proliferation in vitro more than the chemotherapy drug alone. Anecdotal reports from veterinarians have claimed CBD shrunk cancer cells or put dogs into remission.

Behavior: Anxiety, and especially noise reactivity, is a major reason dog owners seek help using CBD. But despite anecdotal reports of its effectiveness, no controlled study so far has shown it to be particularly effective. A study from the University of Western Australia may show promise for aggressive behavior. Shelter dogs with aggressive tendencies exhibited less aggression toward humans when tested after 15 days of CBD administration. In a study from the University of Kentucky, physiological measurements of anxiety in response to noise were not significantly different for CBD versus placebo, and were worse compared to trazodone (a drug commonly prescribed for anxiety). Note, however, that in this study the CBD was administered four to six hours before testing, which may have been too long a waiting period.

Seizures: Lots of anecdotal reports hail CBD’s success combatting seizures in dogs, but the single controlled study delivered moderate results. In this Colorado State University study, dogs given CBD for 12 weeks had 33 percent fewer seizures than those given a placebo, but it didn’t work for every dog. These researchers are now working on a larger trial using higher CBD doses. Note that THC has been reported to cause seizures, so it should never be included in any CBD product for seizure control. In addition, CBD’s effect on cytochrome P450 could interfere with prescribed anti-seizure drugs, so never use it without your veterinarian’s consent.

Other: There’s also evidence from laboratory animals that CBD is effective in promoting bone healing, fighting infection, treating inflammatory bowel disease, slowing degenerative myelopathy, quelling nausea, and relieving pain, but these have yet to be specifically examined in dogs.

Brussels-Griffon-running

How to Choose CBD For Dogs?

With hundreds of CBD products on the market, and little regulation of them, it’s not easy to know which is best. Look for a product with the National Animal Supplement Counsel (NASC) Seal of Quality Assurance, and one that has a third-party certificate of analysis that includes potency, lists all ingredients, and discloses the possible presence of heavy metals, mycotoxins, or pesticides. Avoid edible products formulated for human consumption, which often contain ingredients such as xylitol that are toxic to pets.

Choose products that include other cannabinoids and substances known as terpenes that are also in the cannabis plant. CBD seems to work best when it’s in conjunction with these rather than isolated. But avoid full-spectrum products that include THC.

Aim for about 0.1 to 0.2 mg per kilogram of your dog’s weight, given twice daily by mouth. Work up gradually, but beware that more is not always better with CBD, as sometimes the response is biphasic, meaning that it doesn’t work if you give too little or too much.

Is It Legal?

Many veterinarians are reluctant to suggest CBD, whether because they believe CBD is not yet sufficiently proven helpful or because they fear professional or legal repercussions. CBD products are not approved by the Food and Drug Administration for dogs, but neither are common supplements such as glucosamine or fish oil; nor the majority of human-approved prescription drugs routinely prescribed in veterinary practice.

While it is legal to sell hemp-derived products containing less than 0.3 percent THC, until recently the American Veterinary Medical Association did not approve of veterinarians suggesting any cannabis products, including CBD, for patients. Even now, the law is unclear enough that many veterinarians fear repercussions if something went wrong due to their suggestion of CBD.

While some veterinarians are hesitant to suggest CBD, almost all are eager to discuss it once you bring it up. Of course, some veterinarians are more versed in its pros and cons than others. The main concern is its possible interaction with prescribed drugs.

Overall, the evidence is compelling that CBD can help at least some conditions. The endocannabinoid system is the largest system in the body, and the least explored. Every year brings new discoveries—and new claims. It’s the beginning of a brave new world of health, but as with any new path, expect some wrong turns, dead ends, and false hopes. CBD is not a miracle drug, but it may be the miracle your dog needs.

cbd for pets

Can CBD help my pets?

cbd for pets

Cannabidiol (CBD) products are rapidly growing in popularity, both for humans and pets. With the use of CBD on the rise, pet parents and veterinarians alike are now wondering whether it could be an alternative option for multiple pet health conditions. Early research is promising, but it’s best to work with a veterinarian who is familiar with CBD products if you are looking to give them a try for your pet.

Here, we’ll discuss current CBD research, if it’s safe to use in pets, and whether it could be the right choice for your furry friend.

What is CBD?

The marijuana plant has two main active ingredients — delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the substance responsible for the “high” people experience when they use marijuana. CBD, on the other hand, does not cause a “high” and studies suggest it has a range of potential health benefits.

While restrictions for purchasing CBD products vary from state to state, many people across the U.S. can easily purchase these items both in stores and online. 

But it’s important to note that the FDA hasn’t yet determined whether or not CBD is safe as a food additive, dietary supplement, or treatment in pets. Although there is one FDA-approved human medication containing CBD, no products have been approved in animals. 

What kind of research has been done on the effects of CBD in pets?

Unfortunately, there isn’t much research available when it comes to using CBD in pets. Currently, recommendations are either based on veterinarians’ professional experiences or taken from very small studies. 

As the interest and use of CBD in pets continues to grow, the number and size of these studies will go up as well, providing both veterinarians and pet parents more guidance on how to best use these products.

Is CBD safe for pets?

It’s important to remember that the FDA has not approved any prescription or over-the-counter CBD products for use in animals. This means that the products on the market may not have been tested for safety or effectiveness before being sold. And some companies may promote unsupported medical claims regarding their products that have not been reviewed or approved, either. 

There are also concerns regarding CBD product quality. For example, the product might contain a different amount of CBD than what’s on the label, or it might have contaminants like THC or pesticides. So if you decide to try CBD for your pet, you may have to do some extra digging to find out exactly how the product you’re choosing is made.

If you have any questions, look on the brand’s website or contact the company to ask for their Certificate of Analysis (COA). This public document verifies that the ingredients written on the label are actually in the product. If the company is not able to provide you with the most up-to-date COA, it is not a good idea to purchase a product from that company.

What are the risks of treating my pet with CBD?

The side effects of using CBD in animals are very similar to those experienced by humans. The most common issues include changes to appetite, fatigue, and diarrhea. Typically, the higher the CBD dose you give to your pet, the more likely they will have side effects. 

In most cases, it is not necessary to treat these reactions, as they are generally pretty mild or get better with time. If these side effects don’t get any better or become more severe, you should contact your pet’s veterinarian and keep a close eye on your pet to make sure they don’t hurt themselves.

Can CBD cause my pet to get high?

As mentioned earlier, CBD does not cause a “high” or euphoric feeling. Some people, however, do say it seems their pets are a little out of sorts when they take CBD. If your pet looks like they could be “high” after their dose, there is a reason why this might be happening.

Before purchasing any CBD product, carefully read the label for specific information about its contents. If the product is described as “full spectrum,” this means the product may have up to 0.3% THC in the product — the legal limit according to the Agriculture Improvement Act of 2018. This seemingly small amount could be enough to cause this side effect in your pet, especially if they are extra sensitive to it.

What forms of CBD are available for pets?

If your veterinarian recommends CBD for your pet, there are a range of CBD pet products available, including oils, treats, topical products (lotions, gels, creams), and more. It is often given by mouth or under the tongue. Bottled oils with droppers may be preferable when you first start giving CBD to your pet as it is easier to increase the dose slowly rather than being limited to a fixed amount in a tablet, capsule, or treat.

Are human CBD products safe for pets, or do I need CBD products specifically intended for pets?

Products meant for humans have the same CBD that would be found in products designed for pets. So, human CBD might be OK to give to your pet, but you’ll want to follow any recommendations from your vet. If the product is not made specifically for pets, it is important to read the label to double-check for ingredients that could be toxic to pets like chocolate, certain essential oils, and artificial sweeteners.

Besides being made without these harmful ingredients, pet-specific oral CBD products are usually also flavored with your furry friend in mind — chicken and fish chews, for instance. Be aware that some CBD products have a grassy taste that can make it more difficult to give to your pet. If you find your dog or cat turning their nose up at the product you’ve chosen, try disguising it in a spoonful of peanut butter or your pet’s treat of choice.

What CBD dosage should be used for pets?

Since there aren’t any FDA-approved products for use in animals, and we don’t have many studies looking at safety and efficacy, further research is needed to determine more exact doses. If your veterinarian recommends CBD, make sure to follow their instructions since dosing may vary depending on why you are using the product.

One study looked at the efficacy of CBD oil in helping to alleviate symptoms of osteoarthritis in dogs. Researchers found that 2 mg per kilogram of body weight given twice a day reduced pain without owners reporting any side effects. 

However, blood test results suggested that there may have been some damage to the liver. This is why it’s important that your vet is involved in making sure that your pet is being monitored appropriately.

As with humans who have never taken CBD before, it is important to start your pet on a low dose and raise it slowly. 

For example, you can start with one-quarter or one-half of the dose on the label to see how your pet reacts to a small amount of CBD. If your pet does not experience symptom relief, your vet may have you give another dose of the same amount in 30 to 60 minutes and continue to see how they respond.

Because there isn’t much research available on using CBD in animals, we don’t know the safest maximum dose. It is best to discuss what dose is safe with a veterinarian who has experience using CBD to help your pet’s condition.

What pet health problems might CBD help manage?

CBD has shown benefit for animals in a range of conditions including, but not limited to, inflammatory problemsseizurespain relief, and anxiety. Using CBD for pet health problems is based on the body’s endocannabinoid system (ECS). The goal of the ECS is to achieve and maintain balance of all processes in the body. This is thought to be the reason CBD may have so many potential benefits. 

Keep in mind that every pet’s ECS functions a little bit differently, so CBD may work better for some than others.

Pain

Once absorbed by an animal’s body, CBD may play a role in lowering inflammation and relieving pain. While experts are still learning exactly how CBD may relieve pain, it’s believed to affect the ECS and other nerves that are involved in creating pain sensations. More specifically, studies have shown that reducing joint inflammation relieves osteoarthritis aches and pains in pets.

Anxiety 

Much like humans, many pets experience anxiety, leading to several troublesome behaviors like urinating inappropriately. CBD is thought to ease nervousness and provide feelings of calm. Experts believe this is because CBD may activate some of the same areas of the brain as serotonin — the hormone that helps us feel happy and relaxed.

Seizures 

CBD has been shown to help with epilepsy in dogs by lowering the frequency of seizures when used in combination with traditional antiseizure medications. Although experts don’t fully understand how CBD treats seizures, it is thought to prevent nerves in the brain from firing too much and lower the number of electrolytes believed to have a role in seizure conditions.

A prescription CBD medication called Epidiolex was FDA-approved for two severe seizure conditions called Lennox-Gastaut syndrome and Dravet syndrome in humans in 2018. It is also approved for the treatment of seizures associated with tuberculosis sclerosis complex. However, studies have not been conducted for its use in animals, so it is not recommended to use it in pets.

How can I tell if CBD is helping my pet?

Because our pets cannot tell us whether they are feeling better, the most reliable way to tell if CBD is working is to watch them and their behaviors. After giving a dose of CBD, keep a close eye on your pet to see if their symptoms seem to be improving or not. Depending on the condition your pet has, symptom relief may happen in as soon as 30 minutes or take up to a few weeks of consistent use.

As discussed before, CBD impacts every animal differently. If your vet recommends that you give it a try, you may go through several brands, doses, or forms to find what works for your four-legged companion. But even though finding the right product requires patience, it is worth it to see your pet be their best, happiest self.